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The Citrate Shuttle

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Facebook Twitter Google+ LinkedIn This is a rather brief post explaining one part of multiple physiological pathways, most notably as part of fatty acid synthesis. The citrate shuttle can be narrowed down to 3 steps to allow the transport of ACoA (Acetyl Co-enzyme A) out of the mitochondrial matrix and into the cell cytoplasm, when necessary. The steps below are of the conversion of ACoA to citrate, the movement of citrate across the mitochondrial membrane, and the subsequent lysis of said citrate to reform the initial ACoA needed to be moved.   Step 1: Forming Citrate Firstly, our ACoA will…

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